| 解热镇痛药的发展概况 |
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| 引用本文： | 郝文利,李培锋. 解热镇痛药的发展概况[J]. 动物医学进展, 2006, 27(6): 45-49 |
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| 作者姓名： | 郝文利 李培锋 |
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| 作者单位： | 内蒙古农业大学动物科学与医学学院,内蒙古呼和浩特010018 |
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| 摘 要： | 解热镇痛类药物包括传统的非甾体类抗炎药(COX-1抑制剂)、非传统的非甾体类抗炎药(COX-2抑制剂和一氧化氮释放型NSAIDs)。文章分析其国内外市场状况,并指出临床应用所存在的问题。总结了常用解热镇痛药的不良反应,提出了应用时应注意的事项。预计在今后的一段时期内,研究COX-2选择性抑制剂,发现新结构类型的高活性化合物仍是主攻方向,而且开发NO-NSAIDs也会成为降低NSAIDs的不良反应,增加其疗效的途径之一。
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| 关 键 词： | 解热镇痛药 发展概况 不良反应 |
| 文章编号： | 1007-5038（2006）06-0045-05 |
| 收稿时间： | 2006-01-04 |
| 修稿时间： | 2006-01-04 |
Advance in Non-steroidal Antiinflammatory Drugs |
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| HAO Wen-li,LI Pei-feng. Advance in Non-steroidal Antiinflammatory Drugs[J]. Progress In Veterinary Medicine, 2006, 27(6): 45-49 |
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| Authors: | HAO Wen-li LI Pei-feng |
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| Affiliation: | College of Animal Science and Medicin , Inner Mongolia Agricultrual University, Huhhot , Inner Mongolia, 010018, China |
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| Abstract: | NSAIDs(nonsteroidal anniin flammatory drugs) include traditional NSAIDs(COX-1 inhibitor)and non-traditional NSAIDs(COX-2 inhibitor and NO-NSAIDs).The article analyzed its domestic and international market situation,and pointed out the problems in public application of NSAIDs,summed up their adverse effects,and putted forward many noticeable things during the applying.In many years forward,exploiting COX-2 inhibitor and discovering higher-efficiency compound will be the main direction.NO-NSAIDs will also be the developing way. |
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| Keywords: | NSAIDs development ADRs |
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