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| 副猪嗜血杆菌转铁结合蛋白研究进展 | |
| 引用本文： | 李淑芳,张培君,龚玉梅,侯娜,赵兴绪,贺云霞. 副猪嗜血杆菌转铁结合蛋白研究进展[J]. 动物医学进展, 2012, 33(8): 77-80 |
| 作者姓名： | 李淑芳 张培君 龚玉梅 侯娜 赵兴绪 贺云霞 |
| 作者单位： | 1. 北京市农林科学院畜牧兽医研究所,北京100097;甘肃农业大学动物医学院,甘肃兰州730046 2. 北京市农林科学院畜牧兽医研究所,北京,100097 3. 甘肃农业大学动物医学院,甘肃兰州,730046 |
| 基金项目： | “863”国家高技术研究发展计划项目,国家自然科学基金青年基金 |
| 摘 要： | 副猪嗜血杆菌是猪革拉泽氏病的病原体,该病是近年来严重危害养猪业的细菌性传染病之一,呈世界性分布。副猪嗜血杆菌相关致病性毒力因子的研究目前很少,关于转铁结合蛋白更是鲜为人知。在此对副猪嗜血杆菌转铁结合蛋白的结构、形成机制、影响因素及其免疫原性进行综述,对阐明致病菌的慢性感染机理有一定的生物学意义。 |
| 关 键 词： | 副猪嗜血杆菌 转铁结合蛋白 铁摄取机制 |
Progress on Transferrin-binding Proteins of Haemophilus parasuis |
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| LI Shu-fang , ZHANG Pei-jun , GONG Yu-mei , HOU Na , ZHAO Xing-xu , HE Yun-xia. Progress on Transferrin-binding Proteins of Haemophilus parasuis[J]. Progress In Veterinary Medicine, 2012, 33(8): 77-80 | |
| Authors: | LI Shu-fang ZHANG Pei-jun GONG Yu-mei HOU Na ZHAO Xing-xu HE Yun-xia |
| Affiliation: | 1(1.Institute of Animal Husbandry and Veterinary Medicine of Beijing Academy of Agriculture and Forestry Sciences, Beijing,100097,China;2.Collage of Veterinary Medicine,Gansu Agricultural University,Lanzhou,Gansu,730046,China) |
| Abstract: | Haemophilus parasuis is the etiological agent of Glasser’s disease in pigs,which is responsible for considerable economic losses in the pig industry.The disease is distributed worldwide.Few studies of the virulence factors involved in the pathogenicity of H.parasuis have been reported to date,especially transferrin-binding proteins.Summarizing structure,mechanisms for iron acquisition,impact factor and relevant studies in recent years is important for understanding the chronic infection and antibiotic resistance. |
| Keywords: | Haemophilus parasuis transferrin-binding protein mechanism for iron acquisition |
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