Scleral and corneal xanthomatous inflammation in a gray mouse lemur (Microcebus murinus) |
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Authors: | Charline Alleaume Meryem El Mrini Eve Laloy Julia Marchal Fabienne Aujard Sabine Chahory |
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Affiliation: | 1. Ecole Nationale Vétérinaire d'Alfort, Unité d'Histologie Embryologie et Anatomie pathologique, Université Paris‐Est, Maisons‐Alfort, France;2. Centre National de la Recherche Scientifique, Muséum National d'Histoire Naturelle, Mécanismes Adaptatifs et Evolution, Brunoy, France;3. Ecole Nationale Vétérinaire d'Alfort, UP Ophtalmologie, Université Paris‐Est, Maisons‐Alfort, France |
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Abstract: | Bilateral multifocal corneal opacity was detected in a 4.5‐year‐old male captive gray mouse lemur (Microcebus murinus) without other clinical ocular changes. Histopathological examination revealed a severe diffuse granulomatous scleritis and focal keratitis with intralesional cholesterol, consistent with xanthomatous inflammation. This is the first report of xanthomatous inflammation in a gray mouse lemur. This condition may be the result of systemic factors (lipid metabolism disorders) and/or local predisposing factors such as hemorrhage or inflammation. The pathogenesis in this case could not be fully determined. Further studies on lemurs are required for a better understanding of their lipid metabolism, as well as for diagnosing and evaluating the incidence of xanthomatous inflammation in these species. |
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Keywords: | cornea gray mouse lemur
Microcebus murinus
sclera xanthomatous inflammation |
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