Persistent efficacy of doramectin topical solution against induced infestations of Bovicola bovis and Solenopotes capillatus. |
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Authors: | J E Lloyd R Kumar M A Grubbs J W Waggoner E E Norelius L L Smith A C Brake T L Skogerboe V K Shostrom |
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Institution: | Renewable Resources, University of Wyoming, Box 3354, Laramie, WY 82071-3354, USA. lloyd@uwyo.edu |
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Abstract: | A study was conducted in two locations, Wyoming and Wisconsin, USA, to evaluate the persistent efficacy of doramectin topical solution at a dose rate of 500 microg/kg body weight against artificially induced infestations of Bovicola bovis and Solenopotes capillatus on cattle. At each location, lice-free beef calves were individually housed and randomly allocated to treatment. Both B. bovis and S. capillatus were transferred from untreated donor animals to doramectin-treated cattle at the end of 35, 63, 91 or 126 day post-treatment periods. Cattle treated with a saline pour-on served as the control. Based on the geometric means of lice counts 2 weeks following transfer, the persistent efficacy of a single treatment with doramectin topical solution against induced infestations of B. bovis was 100.0, 100.0, 99.5, and 100.0% at post-treatment days of 35, 63, 91, and 126, respectively. Persistent efficacy against induced infestations of S. capillatus, for the same intervals, were 100.0, 94.9, 86.3, and 74.9%. |
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