| 鸡亚慢性镉中毒及硒颉颃效应的肝脏亚微结构变化 |
| |
| 引用本文： | 蒋成玉,李俊伟,熊永忠,罗公平,由轩,王积海,李金龙,徐世文.鸡亚慢性镉中毒及硒颉颃效应的肝脏亚微结构变化[J].动物医学进展,2005,26(8):72-74. |
| |
| 作者姓名： | 蒋成玉 李俊伟 熊永忠 罗公平 由轩 王积海 李金龙 徐世文 |
| |
| 作者单位： | 中华人民共和国绥芬河出入境检验检疫局,黑龙江,绥芬河,157300;黑龙江省齐齐哈尔市建华区农业局,黑龙江,齐齐哈尔,161000;中国科学院哈尔滨兽医研究所,黑龙江,哈尔滨,150001;中华人民共和国黑龙江出入境检验检疫局,黑龙江,哈尔滨,150001;东北农业大学,黑龙江,哈尔滨,150030 |
| |
| 摘 要： | 为深入探讨镉致动物肝毒性的机制及硒颉颃效应,选用90只100日龄伊沙褐公鸡随机分为3组,通过在日粮中添加一定剂量的镉及硒与镉,建立亚慢性镉中毒或硒颉颃模型;用透射电镜观察亚慢性镉中毒及硒颉颃鸡肝脏的亚微结构变化。证实亚慢性镉中毒可引起鸡肝脏细胞的损伤,造成线粒体、溶酶体等细胞器受损;出现大片细胞萎缩、坏死、凋亡。结果表明,硒能有效地降低镉对细胞器的损伤,减少细胞凋亡数量。
|
| 关 键 词： | 鸡 亚慢性镉中毒 肝脏 硒 亚微结构 |
| 文章编号： | 1007-5038（2005）08-0072-03 |
| 收稿时间： | 2005-04-14 |
| 修稿时间： | 2005年4月14日 |
Hypo- ultrastructural Changes in Liver of Cocks Caused by Subchronic Cadmium Toxication and Selenium Antigonism |
| |
| JIANG Cheng-yu,LI Jun-wei,XIONG Yong-zhong,LUO Gong-ping,YOU Xuan,WANG Ji-hai,LI Jin-long,XU Shi-wen.Hypo- ultrastructural Changes in Liver of Cocks Caused by Subchronic Cadmium Toxication and Selenium Antigonism[J].Progress In Veterinary Medicine,2005,26(8):72-74. |
| |
| Authors: | JIANG Cheng-yu LI Jun-wei XIONG Yong-zhong LUO Gong-ping YOU Xuan WANG Ji-hai LI Jin-long XU Shi-wen |
| |
| Abstract: | In order to further study the mechanism of liver toxication caused by cadmiun and the role of selenium antagonism to cadmium, ninety 100-day-old cocks were used as experimental animals, and a certain concentrational cadmium and selenium were added in the basic diet.The hypo-ultrastructural changes of liver demonstrated that cadmium can make hepatocyte damage, cytoplasm atrophy, endoplasmic reticulum loose and fusion with membrane, ribosome,mitochondria,chromatin and nucleus atrophy.Many hepatocytes become necrosis and apoptotic bodies, then they were phagocytized by phagocytic cells.Selenium can reduce the effect of cadmium damage on organelles. |
| |
| Keywords: | cock subchronic cadmium toxiaction liver selenium hypo-ultrastructure |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
