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正交试验法优选大黄超微粉生产工艺研究
引用本文:刘永录,张国祖,李宇伟,连瑞丽,于瑞.正交试验法优选大黄超微粉生产工艺研究[J].中兽医医药杂志,2010,29(5):44-46.
作者姓名:刘永录  张国祖  李宇伟  连瑞丽  于瑞
作者单位:1. 郑州牧业工程高等专科学校药物工程系,河南郑州,450011
2. 河南省康星药业有限公司
基金项目:河南省教育厅自然科学研究计划项目,校企合作开发项目-超微粉碎中药制剂研究 
摘    要:目的:优化大黄超微粉的生产工艺。方法:本研究采用正交试验法对大黄超微粉生产工艺过程进行优化,考察了不同生产工艺对大黄超微粉过筛率的影响。结果:正交试验优选出大黄超微粉碎生产工艺的最佳条件,生产时水分含量为3%,研磨时间为20 min,棒料比为20∶1。结论:以优化工艺所得大黄超微粉的过筛率高,有利于工业生产。

关 键 词:大黄  超微粉碎  正交试验  生产工艺

Optimization on the producing process for Rhubarb ultra-structural powder by orthogonal design
Institution:LIU Yong-lu,ZHANG Guo-zu,LI Yu-wei,LIAN Rui-li(Medicinal Engineering Department,Zhengzhou College of Animal Husbandry and Engineering,Zhengzhou Henan 450011,China)
Abstract:Objective: To optimize the producing process for rhubarb ultra-structural powder.Methods: An orthogonal design was adopted to optimize the producing process for rhubarb ultra-structural powder.The different producing technology on the effect of sieving rate was evaluated.Results: The optimum conditions for rhubarb ultra-structural powder by orthogonal test optimized process were as follows: 3% water in the process of production for 20 min by milling with ratio of bar to water of 20∶1.Conclusion: The result of this experiment is reliable.The sieving rate of rhubarb ultra-structural powder produced by the optimized process is high.So it is propitious to the batch production.
Keywords:rhubarb  super fine crushing  orthogonal design  producing process
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