新鲜羊膜移植术治疗眼表烧伤晚期并发症的临床研究

目的：研究新鲜羊膜移植术治疗眼表烧伤晚期并发症的可行性、手术方法和临床效果。方法：眼表烧伤晚期病例18例(18眼)，其中角膜血管翳8例，角膜溃疡7例，睑球粘连3例，采用新鲜羊膜移植治疗。手术方法：单层与多层羊膜移植或联合眼睑成形，角膜缘干细胞移植术。术后随访6～12个月。结果：18例术后植片均未见急性排斥反应，术后4～6周稳定愈合；13眼视力有不同程度提高。18眼中有17眼治愈。结论：新鲜羊膜是治疗眼表烧伤晚期并发症的有效方法。

Fresh amniotic membrane transplantat ion in late complications of ocular surface burn

Objective:To study the feasibility,operative method and therapeutic efficacy of fresh amniotic membrane transplantation (AMT) in late complications of ocular surface burn.Methods:Eighteen eyes of 18 patients with late complications of ocular surface burn were subjected to AMT via single layer and multilayer AMT or combined reconstruction of eyelid and corneal limbal stem transplantation;eight patients had corneal pannus,seven had corneal ulcer and three had symblepharon.All patients were followed up for 6 12 months.Results:Acute rejection did not occur in all patients.Epithelium healed above all corneal ulcers within 4 6 weeks.Seventeen patients were cured,and visual acuity was improved in 13 patients.Conclusion:Fresh AMT is useful for treating late complications of ocular surface burn.