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c9,t11-CLA对人结肠癌细胞(Caco-2)的抑制作用
引用本文:陈燕,黄桂东,钟先锋,唐浩国. c9,t11-CLA对人结肠癌细胞(Caco-2)的抑制作用[J]. 农产品加工.学刊, 2009, 0(6). DOI: 10.3969/j.issn.1671-9646(X).2009.06.008
作者姓名:陈燕  黄桂东  钟先锋  唐浩国
作者单位:1. 南昌大学,中德联合研究院,食品科学教育部重点实验室,江西,南昌,330047
2. 南昌大学,中德联合研究院,食品科学教育部重点实验室,江西,南昌,330047;河南科技大学,食品科学与生物工程学院,河南,洛阳,471003
3. 河南科技大学,食品科学与生物工程学院,河南,洛阳,471003
基金项目:河南科技大学校青年基金 
摘    要:采用体外细胞培养方法,通过MTT实验,研究了c9,t11-CLA(Conjugated Linoleic acid,CLA)在不同浓度,(0,25,50,100,200μmol/L)、不同作用时间(1,2,3,4 d)下,对人结肠癌细胞Caco-2增殖的影响。结果表明,c9,t11-CLA抑制了Caco-2细胞的增殖,且对Caco-2细胞增殖的抑制作用与浓度和作用时间密切相关。

关 键 词:c9,t11-CLA  人结肠癌细胞Caco-2  增殖  抑制

Inhibitory Effect of c9,t11-CLA on Human Colon Adenocarcinoma Cell Line Caco-2
Chen Yan,Huang Guidong,Zhong Xianfeng,Tang Haoguo. Inhibitory Effect of c9,t11-CLA on Human Colon Adenocarcinoma Cell Line Caco-2[J]. Nongchanpin Jlagong.Xuekan, 2009, 0(6). DOI: 10.3969/j.issn.1671-9646(X).2009.06.008
Authors:Chen Yan  Huang Guidong  Zhong Xianfeng  Tang Haoguo
Affiliation:1.Sino-German Joint Research Institute;Key Laboratory of Food Science of Ministry of Education;Nanchang University;Nanchang;Jiangxi 330047;China;2.College of Food Science and Bioengineering;He'nan University of Science and Technology;Luoyang;He'nan 471003;China
Abstract:The test was done by means of MTT assay in cell culture to observe the effects of different concentrations(0,25,50,100,200 μmol/L) of c9,t11-CLA on the proliferation of Caco-2 cell line in varying action time(1,2,3,4 d).The results showed that the Caco-2 cell proliferation could be inhibited by c9,t11-CLA.The activity was also closely related to the treatment time and concentration.
Keywords:c9  t11-CLA
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