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Two Cases of Cutaneous Diphtheria Associated with Occupational Pig Contact in Germany
Authors:R Konrad  T Schmidt‐Wieland  S Hörmansdorfer  M Eddicks  A Sing
Institution:1. National Consiliary Laboratory for Diphtheria, , Oberschlei?heim, Germany;2. Bavarian Health and Food Safety Authority, , Oberschlei?heim, Germany;3. Labor Dr. Gaertner, , Ravensburg, Germany;4. Clinic for Swine, Ludwig‐Maximilians‐University Munich, , Oberschlei?heim, Germany
Abstract:In 2010, two independent cases of cutaneous diphtheria caused by toxigenic C. ulcerans were identified in Germany. Both patients had intense occupational contact with pigs. Diagnostic work‐up comprising biochemical differentiation, rpoB sequencing, matrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometry (MALDI‐TOF) analysis, real‐time tox PCR and Elek test as well as public health measures including an intensified source tracing involving 83 asymptomatic pigs of an associated pig farm are presented.
Keywords:Diphtheria     Corynebacterium ulcerans     zoonosis  outbreak investigation
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