Urine production,renal function,and drug monitoring in the equine intensive-care unit |
| |
| Affiliation: | 1. San Giovanni Hospital, Rome, Italy;2. Centro per la Lotta Contro L’Infarto–CLI Foundation, Rome, Italy;3. Misericordia Hospital, Grosseto, Italy;4. Central Clinical Hospital of the Ministry of Interior, Warsaw, Poland;5. Sandro Pertini Hospital, Rome, Italy;6. Ospedale Civile Ferdinando Veneziale, Isernia, Italy;7. GVM Care and Research, E.S. Health Science Foundation, Cotignola, Italy;8. Columbia University Medical Center and the Cardiovascular Research Foundation, New York, NY;1. Department of Animal Medicine and Surgery, Faculty of Veterinary Medicine, Cardenal Herrera University, Valencia, Spain;2. Department of Animal Medicine and Surgery, Faculty of Veterinary Medicine, University of Córdoba, Spain;1. Icahn School of Medicine at Mount Sinai, New York, NY, USA;2. Cardiovascular Research Foundation, New York, NY, USA |
| |
| Abstract: | Monitoring urine production, renal function, and drug concentration in plasma can be extremely valuable in the management of critically ill horses. Renal failure, either hemodynamically-mediated or nephrotoxic, is a very common problem in horses either at admission or during critical care treatment. Prompt treatment is required in order to prevent the renal failure from becoming a life-threatening problem. Drug monitoring is not only used to decrease the risk of nephrotoxic renal failure, but should be used to confirm that therapeutic blood levels of a drug are present. Monitoring therapeutic but less than toxic levels is particularly important in critically ill horses since the pharmacokinetics of many drugs is affected by the degree of illness. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
