Magnitude of mitral valve closure plays a pivotal role in enhancing the
forward blood flow during cardiac massage in dogs with ventricular
fibrillation |
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| Authors: | Ai GOTO Ryuichi KAMBAYASHI Hiroko IZUMI-NAKASEKO Yoshinori TAKEI Shinichi KAWAI Akio MATSUMOTO Keith G. LURIE Atsushi SUGIYAMA |
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| Affiliation: | 1)Department of Pharmacology, Faculty of Medicine, Toho University, Tokyo, Japan;2)Department of Inflammation & Pain Control Research, Faculty of Medicine, Toho University, Tokyo, Japan;3)Department of Aging Pharmacology, Faculty of Medicine, Toho University, Tokyo, Japan;4)Department of Emergency Medicine, University of Minnesota Medical School, Minneapolis, USA |
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| Abstract: | Motion of mitral valve during cardiac massage was examined using beagle dogs with ventricular fibrillation (n=4). Active compression-decompression cardiac massage (ACD-CM) exhibited greater peak aortic pressure than standard cardiac massage (S-CM), reverse of which was true for peak pulmonary capillary wedge pressure in each animal. Accordingly, peak aortic pressure was greater than peak pulmonary capillary wedge pressure with ACD-CM, whereas its reverse was true with S-CM. Transesophageal echocardiography revealed that mitral valve was incompletely closed with S-CM with showing regurgitation. The valve was more effectively closed during ACD-CM. These results indicate that effective closure of mitral valve during cardiac massage may increase forward blood flow, supporting “cardiac pump theory” rather than “thoracic pump theory” as a principle in dogs. |
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| Keywords: | active decompression cardiac massage cardiac pump theory mitral valve closure transesophageal echocardiography |
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