三种抗球虫药对鸡球虫病的对比疗效

为评价药物阿德呋啉对艾美耳球虫的治疗效果,本试验设70 mg/kg阿德呋啉组、121mg/kg莫能菌素组和125 mg/kg尼卡巴嗪组3个药物试验组,以及阳性和阴性对照组。除阴性对照组外,其余全部试验鸡每只接种球虫孢子化卵囊5.2万个,根据成活率、相对增重率、卵囊值、病变值计算抗球虫指数(Anticoccidial Index,ACI),进而判定药物的疗效。结果显示,121 mg/kg莫能菌素组ACI为115.6,在120以下,不宜作抗球虫药;125 mg/kg尼卡巴嗪组ACI为137.2,在120～160之间,抗球虫效力低;70 mg/kg阿德呋啉组ACI为192.9,为高效抗球虫药。

Efficacy Comparison of Three Anticoccidial Drugs on Coccidiosis in Chickens

In order to evaluate the efficacy of ardfuline against Eimeria, the experiment set up three drug test groups ：ardfuline for 70 mg/kg, monensin for 121 mg/kg and nicarbazin for 125 mg/kg,besides positive and negative control groups. Except the negative control group, each chick was vaccinated 5.2× 10^4 sporulated Eimeria coccidia oocysts. According to survival rate, relative body weight gain, oocyst value and lesion value,the anticoccidial index （ACI） was calculated to judge the effect. The results showed that the ACI of 121 mg/kg monensin group was 115.6, unsuitable for anticoccidial drugs,the ACI of nicarbazin was 137.2 with low anticoccidial effect,and the ACI of ardfuline group was 192.9, which was more than 180.0 to be the efficient anticoccidial drug.