Two new iridoid glucosides from Hedyotis diffusa |
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| Authors: | Yongyong Zhang Yan Chen Chunlin Fan Wencai Ye Jiabo Luo |
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| Affiliation: | 1. Laboratory of Bioactive Natural Products Chemistry, College of Pharmaceutical Sciences Zhejiang University, Hangzhou 310058, PR China;2. Key Laboratory of Research of TCM and New Drug, Southern Medical University, Guangzhou 510515, PR China;3. Pharmacodynamics and New Drug Development, College of Pharmaceutical Sciences Zhejiang University, Hangzhou 310058, PR China;4. Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Jinan University, Guangzhou 510632, PR China |
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| Abstract: | Two new iridoid glucosides, named diffusosides A and B, were isolated from the aerial part of Hedyotis diffusa Willd. Their structures were elucidated by 1D-, 2D-NMR spectroscopic analysis and HRESIMS. These two compounds showed no cytotoxic activity against SMMC-7721, SW480, SW620, Bel7402, and HepG2 cells. |
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| Keywords: | Hedyotis diffusa Iridoid glucosides Diffusoside A Diffusoside B |
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