In vitro TAXOL production,by Pestalotiopsis breviseta — A first report |
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| Authors: | Govindarajan Kathiravan Vithiyanathan Sri Raman |
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| Affiliation: | 1. Department of Biotechnology, Vels University, Pallavaram, Chennai–6OO 117, Tamilnadu, India;2. Department of Industrial Chemistry and Chemistry, Vels University, Pallavaram, Chennai–6OO 117, Tamilnadu, India |
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| Abstract: | Coelomycetous fungi were screened for the production of TAXOL. TAXOL production of Pestalotiopsis breviseta fungi is confirmed by Ultra Violet (UV) spectroscopic analysis, Infra Red (IR) analysis, high performance liquid chromatography (HPLC), nuclear magnetic resonance (NMR) and LC–MASS spectroscopy. TAXOL isolated from the P. breviseta fungus was identical with authentic TAXOL and produces 0.064mg/L (0.128% dry weight of fungal mat). |
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| Keywords: | Taxol Pestalotiopsis breviseta LC&ndash MASS NMR |
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