New biologically active compounds from Kenyan propolis |
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| Authors: | Assya Petrova Milena Popova Christina Kuzmanova Iva Tsvetkova Hristo Naydenski Eliud Muli Vassya Bankova |
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| Institution: | 1. Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, Acad. G. Bonchev str. Bl. 9, 1113 Sofia, Bulgaria;2. Institute of Microbiology, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria;3. International Centre of Insect Physiology and Ecology (icipe), P. O. Box 30772, Nairobi, Kenya |
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| Abstract: | From propolis samples from Kenya, two new arylnaphtalene lignans were isolated, tetrahydrojusticidin B 1 and 6-methoxydiphyllin 2, along with four known phenolic compounds 5–8, found for the first time in propolis. The structures of the compounds were elucidated based on their spectral properties. The geranylstilbenes 7 and 8 demonstrated antibacterial activity against S. aureus, and the geranylflavon macarangin 6 possessed antiradical activity against DPPH radicals. |
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| Keywords: | Propolis Prenylated stilbenes Arylnaphtalene lignans Macaranga schweinfurthii |
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