A new triglucosylated naphthalene glycoside from Aloe vera L. |
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| Authors: | Qing-Yun Yang Chun-Suo YaoWei-Shuo Fang |
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| Institution: | Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education and Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, 1 Xiannongtan Street, Beijing 100050, PR China |
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| Abstract: | A new triglucosylated naphthalene derivative, named aloveroside A (1), together with two known anthraquinone dimers and two 6-phenyl-2-pyrone derivatives, was isolated from the Aloe vera ethanolic extracts. The structure of 1 was established as 1-(((4-(1-O-β-D-glucopyranosyl -(1→4)-β-D-xylopyranoside)-hydroxymethyl)-1-hydroxy-8-O-α-L-rhamnopyranoside)naphthalene-2-yl)-ethanone by means of spectroscopic evidences and chemical methods. All these compounds were tested for their BACE inhibitory activity but no significant activities were found. |
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| Keywords: | Aloe vera L Naphthalene glycoside Aloveroside A |
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