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Constituents from fruits of Cupressus sempervirens
Authors:Preeti Rawat  Mohammad F Khan  Manmeet Kumar  Akhilesh K Tamarkar  Arvind K Srivastava  Kamal R Arya  Rakesh Maurya
Institution:1. Medicinal and Process Chemistry Division, Central Drug Research Institute, Lucknow-226 001, India;2. Biochemistry Division, Central Drug Research Institute, Lucknow-226 001, India;3. Botany Division, Central Drug Research Institute, Lucknow-226 001, India
Abstract:Two new phenolic glycosides (1, 2), along with fourteen known compounds (316) have been isolated from the fruit of Cupressus sempervirens. The structures of these compounds were determined by spectroscopic analysis and were evaluated for their inhibitory activity against glycogen phosphorylase and glucose-6-phosphatase enzymes. Compounds 14 showed a moderate inhibition against glucose-6-phosphatase and 15 against glycogen phosphorylase enzymes.
Keywords:Cupressus sempervirens  Cupressaceae  Glucose-6-phosphatase  Glycogen phosphorylase  Phenolic glycoside
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