| 鸡腿蘑对小鼠骨髓细胞的遗传毒性研究 |
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| 引用本文： | 孟国良 李凤玲. 鸡腿蘑对小鼠骨髓细胞的遗传毒性研究[J]. 中国食用菌, 1997, 16(3): 35-36 |
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| 作者姓名： | 孟国良 李凤玲 |
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| 作者单位： | 郑州牧业工程高等专科学校 |
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| 摘 要： | 应用小鼠骨髓细胞姐妹染色单体交换（ＳＣＥ）及微核试验对鸡腿蘑进行遗传毒理检测。结果表明：用鸡腿蘑浸提液处理过的小鼠，其骨髓细胞微核率及ＳＣＥ频率与阴性对照组比较差异不显著（Ｐ＞０．０５），而与阳性对照组相比，差异极显著（Ｐ＜０．０１）。这表明，鸡腿蘑无致畸变作用
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| 关 键 词： | 鸡腿蘑 姐妹染色单体交换 微核试验 |
Genetic Toxicity of Coprinus comatus on Mouse Bone Marrow Cells |
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| Meng Guoliang et al. Genetic Toxicity of Coprinus comatus on Mouse Bone Marrow Cells[J]. Edible Fungi of China, 1997, 16(3): 35-36 |
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| Authors: | Meng Guoliang et al |
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| Affiliation: | Journal of Zhengzhou College of Animal Husbandry 450045 |
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| Abstract: | By means of sister chromatid exchange method (SCE),micronucleus test of bone marrow cells, genetic toxicity of Coprinus comatus was evaluated in mice. The results showed that, there are no significant differences in SCE frequency and micronucles frequency between the Coprinus comatus group and the negative control group (P>0 05). However there are a very significant difference between the Coprinus comatus group and the positive control group. These showed that Coprinus comatus has no mutagenic action. |
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| Keywords: | Coprinus comatus Sister chromatid exchange (SCE) Micronucleus test |
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