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Heat-labile serum factor required for immunofluorescence of polyoma tumor antigens |
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| Authors: | K K Takemoto R A Malmgren K Habel |
| Abstract: | The immunofluorescent demonstration of polyoma tumor antigens in tumor cells requires a heatlabile serum component. With unheated hamster tumor serum, specific fluorescence was observed in polyoma-transformed hamster, mouse, and rat tumor cells. Heated serum usually gave little or no reactivity; the activity of such heated serum could be restored simply by the addition of fresh normal unheated hamster serum. |
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