| 苦马豆素的来源及分离方法进展 |
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| 引用本文： | 吴旭锦,杨鸣琦,白春黎,周宏超. 苦马豆素的来源及分离方法进展[J]. 动物医学进展, 2005, 26(5): 41-44 |
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| 作者姓名： | 吴旭锦 杨鸣琦 白春黎 周宏超 |
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| 作者单位： | 西北农林科技大学动物科技学院,陕西,杨陵,712100;陕西省榆林农业学校,陕西,榆林,719000 |
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| 基金项目： | 国家自然科学基金;陕西省自然科学基金 |
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| 摘 要： | 苦马豆素(SW)是疯草的主要毒性成分,研究表明它具有明显的抗肿瘤活性。目前,SW作为一种崭新的抗癌药物倍受关注其实验室分离技术已取得很大进展,并已通过索氏抽提、柱层析、离子交换层析、高效液相色谱、萃取等方法分别从苦马豆属、棘豆属、黄芪属的多种植物及豆类丝核菌中分离出了SW。文章对SW来源和的分离进行了综述。
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| 关 键 词： | 苦马豆素 分离 |
| 文章编号： | 1007-5038(2005)01-0041-04 |
| 修稿时间： | 2004-08-06 |
Progress in the Method for Swainsonine Source and Separating Method |
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| WU Xu-jin,YANG Ming-qi,BAI Chun-Li,ZHOU Hong-Chao. Progress in the Method for Swainsonine Source and Separating Method[J]. Progress In Veterinary Medicine, 2005, 26(5): 41-44 |
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| Authors: | WU Xu-jin YANG Ming-qi BAI Chun-Li ZHOU Hong-Chao |
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| Abstract: | Swainsonine is the main toxicity composition of locoweed. The result of research shows it has obvious anti-tumor activion. In recent years, swainsonine is got the tremendous concern as a new kind of anti-cancer medicine. Currently, the laboratory technique separating swainsonine has already made great progress.swainsonine was successfully separated from swainsonine canesces,Oxytropis,Astragalus plants and Rhizoctonia leguminicola by Soxhlet extraction,column chromatography,ion exchange chromatography,high performance liquid chromatography and so on. The article summarizes the separating techniques of swainsonine. |
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| Keywords: | swainsonine separation |
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