| Abstract: | Radiolabelled fatty acids, when injected intradermally into cattle skin, were largely incorporated into the triglyceride and phospholipid fractions of the sebaceous gland lipids. Linoleic acid was incorporated into the triglycerides to a greater extent than oleic or palmitic acids, whereas the phospholipids had a greater affinity for palmitic acid. The peak uptake of linoleic acid into the glandular triglyceride fraction was at about 61 hours compared with 52 hours and three hours for oleic and palmitic acids. Radioactively 14C labelled triglycerides appeared on the skin surface within one day of intradermal injection of 14C linoleic acid. At an ambient temperature of 20 degrees C, a single output-peak occurred at nine days while at 35 degrees C two peaks at four and eight to nine days were observed. From the data an estimate of 6.5 days for the mean storage time of sebum triglycerides in the hair follicle canal at 20 degrees C has been made. |
