畜炎宁治疗奶牛子宫内膜炎疗效试验

奶牛子宫内膜炎是奶牛产后主要由于细菌感染而引起的常见产科慢性、常发性疾病，给奶牛养殖业造成很大的经济损失。采集患子宫内膜炎奶牛产后阴道分泌物进行细菌分离鉴定和药敏试验，了解子宫内膜炎病例中病原菌的种类及耐药情况。在临床试验中，选用海正畜炎宁与野菊花、金银花、蒲公英等为主要成分的中草药进行对比疗效试验，通过治疗前后子宫及阴道恢复情况来确定治疗效果。试验结果证实：该牛场引起子宫内膜炎的细菌主要是以大肠杆菌、绿脓杆菌、蜡样芽孢菌、链球菌和枯草芽孢杆菌为主，单一感染所占比例为24．4％，混合感染所占比例为75．6％；药敏试验结果表明海正畜炎宁最为敏感，临床试验也证实：肌肉注射畜炎宁组有效率最高，达到78．75％；子宫灌注畜炎宁组达到75％；而对照组子宫灌注组仅为50％，因此，在治疗牛子宫内膜炎时，海正畜炎宁可作为治疗药物的首选。

Therapeutic Efficacy Experiments of Xuyanning in Treating Endometritis of Dairy Cows

Cow endometritis was a common puerperal disease caused by bacterial infections,which causes economic losses.To realize the varieties and drug resistance of the clinical case of pathogenic bacteria of endometritis,bacteria of postpartum vaginal secretions of dairy cows of suffering endometritis was isolated and identified as well as drug sensitivity tested.In clinical trials,HaiZheng Xuyanning and the Chinese herbal medicine which the main component was wild chrysanthemum,honeysuckle and dandelion were selected as comparative efficacy trial to determine the effects through the uterine and vaginal recovery before and after the treatment.The results showed that the bacteria of endometritis was mainly Escherichia coli,Pseudomonas,Bacillus cereus,Streptococcus pneumoniae and Bacillus subtilis.Single infection proportion was 24.4% and mixed infection proportion was 75.6%.Drug susceptibility test results indicated that Xuyanning was the most sensitive.Clinical trials confirmed that Xuyanning group of intramuscular injection had the highest efficiency which was 78.75%.Xuyanning group of uterine perfusion was 75% while the control group was only 50%.Therefore,Xuyanning could be used as the first choice of therapeutic drug in the treatment of cow endometritis.