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| 水泡性口炎病毒感染BHK-21细胞的超微结构改变 | |
| 引用本文： | 褚秀玲,宋德光,苏建青,韦旭斌,高丰.水泡性口炎病毒感染BHK-21细胞的超微结构改变[J].中国兽医学报,2006,26(3):265-267. |
| 作者姓名： | 褚秀玲 宋德光 苏建青 韦旭斌 高丰 |
| 作者单位： | 1. 吉林大学,畜牧兽医学院,吉林,长春,130062;河北北方学院,动物医学系,河北,张家口,0751312 2. 吉林大学,畜牧兽医学院,吉林,长春,130062 3. 河北北方学院,动物医学系,河北,张家口,0751312 |
| 摘 要： | 应用起薄切片技术对水泡性口炎病毒（VSV）在BHK-21细胞上的形态发生和早期发育进行了观察。结果表明，VSV能导致BHK-21细胞圆缩．胞浆严重空泡化，线粒体嵴断裂及空泡化；病毒在细胞浆内复制．增殖．在细胞膜上以出芽方式获得囊膜而成热。 |
| 关 键 词： | 水泡性口炎病毒 BHK-21细胞 细胞病变 超微结构 |
| 文章编号： | 1005-4545(2006)03-0265-03 |
| 收稿时间： | 2005-04-28 |
| 修稿时间： | 2005年4月28日 |
Ultrastructural Changes of BHK-21 Cell Inoculated with Vesicular Stomatitis Virus |
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| CHU Xiu-ling,SONG De-guang,SU Jian-qing,WEI Xu-bin,GAO Feng.Ultrastructural Changes of BHK-21 Cell Inoculated with Vesicular Stomatitis Virus[J].Chinese Journal of Veterinary Science,2006,26(3):265-267. | |
| Authors: | CHU Xiu-ling SONG De-guang SU Jian-qing WEI Xu-bin GAO Feng |
| Institution: | 1. College of Animal Science and Veterinary Medicin ,Jilin University ,Changchun 130062,China; 2. Department of Animal Medicine ,Hebei Northern College ,Zhangjiakou 075131 ,China |
| Abstract: | The morphopoiesis and progenesis of the vesicular stomatitis virus in baby hamster kidney cell-21(BHK-21) were observed by using electron microscope. The results showed that BHK-21 cell became round in shape; a lot of vacuoles occurred in its cytoplasm; the mitochondria vacuolated and the ridge of mitochondria ruptured. Virus replicated and then multiplied within the cytoplasm. It was matured through obtaining the capsid from cellular membrane via budding. |
| Keywords: | vesicular stomatitis virus BHK-21 cells cytopathogenic effect(CPE) ultrastructural features |
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