Effects of anti-glaucoma drugs on resistive index of the medial long posterior ciliary artery using color Doppler imaging in Beagle dogs |
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Authors: | Hojung Choi Youngwon Lee Seongchan Yeon Hyojong Lee Heechun Lee |
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Institution: | 1Department of Veterinary Medical Imaging, College of Veterinary Medicine, Chungnam National University, Daejeon 305-764, Korea.;2Research Institute of Life Sciences, Gyeongsang National University, Jinju 660-701, Korea. |
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Abstract: | Color Doppler imaging (CDI) was carried out to evaluate the effects of anti-glaucoma drugs on ophthalmic circulation using CDI-derived resistive index (RI) values. CDI was performed on nine Beagle dogs, and RI values were calculated for the medial long posterior ciliary artery before and after the administration of anti-glaucoma drugs. A significant increase in RI values was found after topical administration of levobunolol (p < 0.05) or dipivefrin (p < 0.05). Pilocarpine showed no effects on RI values after topical administration. The results suggest that some anti-glaucoma drugs could affect ophthalmic blood flow. |
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Keywords: | anti-glaucoma drugs color Doppler imaging dogs resistive index |
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