| Abstract: | A study was made of the neurotoxic effects of the pyrethroid insecticide allethrin on the peripheral nervous system of the frog by means of electrophysiological techniques. The principal action of allethrin is to induce repetitive activity, not only in sensory nerve fibres and in sense organs, but also in the distal part of the motor fibres, leading to pronounced repetition in the motor end-plate. Measured by the number of repetitive nerve impulses allethrin shows a marked negative temperature coefficient of activity in the lateral-line sense organ and in the motor nerve terminal. |
