Preferential decay of passively acquired immunoglobulins recognizing shared gram-negative core antigens in neonatal swine |
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| Authors: | J W Tyler J S Cullor V L Douglas W L Smith K M Parker |
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| Institution: | Department of Clinical Pathology, School of Veterinary Medicine University of California, Davis 95616. |
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| Abstract: | Serum immunoglobulins of the IgG isotype recognizing common gram-negative cell core epitopes were serially measured by use of a direct ELISA on blood obtained from 10 neonatal swine. An R-mutant Escherichia coli (strain J5) was used as a plate antigen. Total serum IgG was measured by use of radial immunodiffusion. Half-lives of core antigen-specific IgG (6.81 days) and total serum IgG (14.85 days) were dramatically different (P less than 0.01). |
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