Current knowledge on porcine regulatory T cells |
| |
Authors: | Käser Tobias Gerner Wilhelm Mair Kerstin Hammer Sabine E Patzl Martina Saalmüller Armin |
| |
Affiliation: | Institute of Immunology, Department of Pathobiology, University of Veterinary Medicine Vienna, Veterin?rplatz 1, 1210 Vienna, Austria. tobias.kaeser@vetmeduni.ac.at |
| |
Abstract: | Regulatory T cells (Tregs) are known in humans and mice from last 15 years, and several studies led to a detailed knowledge on their phenotype, functions, and role in various immune reactions. In swine, the existence of Tregs was first demonstrated in 2008 and research is still at the beginning. Nevertheless, basic information regarding phenotype, mechanisms and targets of suppression, as well as implications in transplantation and some diseases are available. Purpose of this review is to give a brief summary of the current knowledge about porcine Tregs. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|