| 汇集滤白细胞血小板的研制及临床应用 |
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| 引用本文： | 陈龙菊,程亚媛,刘义明,梁其隆,孙天钢,周明欣.汇集滤白细胞血小板的研制及临床应用[J].湛江医学院学报,2009,27(3):242-244. |
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| 作者姓名： | 陈龙菊 程亚媛 刘义明 梁其隆 孙天钢 周明欣 |
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| 作者单位： | 陈龙菊,程亚媛,梁其隆,CHEN Long-ju,CHENG Ya-yuan,LIANG Qi-long(广东省茂名市中心血站,广东茂名,525000);刘义明,LIU Yi-ming(广东省湛江市第二人民医院,广东湛江,524003);孙天钢,SUN Tian-gang(广东省高州市人民医院输血科,广东高州,525200);周明欣,ZHOU Ming-xin(广东省高州市中医院血库,广东高州,525200) |
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| 摘 要： | 目的 评价汇集滤白细胞血小板的质量和临床效果。方法用白膜层法制备手工浓缩血小板，再以60～70mL／min的速度对汇集血小板进行白细胞过滤。30袋汇集滤白细胞血小板过滤前后分别进行血小板含量、白细胞残留量检测和细菌培养，并观察87例出血患者（血液病16例、非血液病71例）输注后24h疗效。结果30袋汇集滤白细胞血小板过滤前后血小板含量差异无统计学意义（P〉0．05），白细胞残留量差异有统计学意义（P〈0．01），细菌培养均为阴性。非血液病出血患者输注汇集滤自细胞血小板的有效率是85．9％，而血液病患者输注有效率是75．0％。结论汇集滤白细胞血小板质量指标均达到单采血小板国家质量标准，临床应用效果良好。
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| 关 键 词： | 白细胞过滤 汇集血小板 临床应用 白膜层法 |
Preparation and clinical application of leukocyte-filtrated platelet concentrate |
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| CHEN Long-ju,CHENG Ya-yuan,LIU Yi-ming,LIANG Qi-long,SUN Tian-gang,ZHOU Ming-xin.Preparation and clinical application of leukocyte-filtrated platelet concentrate[J].Journal of Guangdong Medical College,2009,27(3):242-244. |
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| Authors: | CHEN Long-ju CHENG Ya-yuan LIU Yi-ming LIANG Qi-long SUN Tian-gang ZHOU Ming-xin |
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| Institution: | CHEN Long-ju1,CHENG Ya-yuan1,LIU Yi-ming2,LIANG Qi-long1,SUN Tian-gang3,ZHOU Ming-xin4(1.Central Blood Station of Maoming,Maoming 525000,China) |
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| Abstract: | Objective To evaluate the quality and clinical effectiveness of leukocyte-filtrated platelet concentrate.Methods The platelet concentrate was prepared manually by buffy coat,and then filtrated at the speed of 70 mL/min for removal of leukocyte.Thirty bags of platelet concentrates were detected by platelet and WBC count and bacterial culture before and after leukocyte filtration.The 24-h clinical efficacy in 87 patients with hemorrhagic disease(hematologic diseases,16;non-hematologic diseases,71)was observed... |
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| Keywords: | leukocyte filtration platelet concentrate clinical application buffy coat |
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