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精氨酸和精氨酸生素对断奶仔猪氧化应激的影响
引用本文:高运苓,吴信,周锡红,李铁军,耿梅梅,黄瑞林,印遇龙.精氨酸和精氨酸生素对断奶仔猪氧化应激的影响[J].农业现代化研究,2010,31(4):484-487.
作者姓名:高运苓  吴信  周锡红  李铁军  耿梅梅  黄瑞林  印遇龙
作者单位:1. 中国科学院亚热带农业生态研究所,农业生态过程重点实验室,湖南省畜禽健康养殖工程技术研究中心,湖南,长沙410125;中国科学院研究生院,北京100049
2. 中国科学院亚热带农业生态研究所,农业生态过程重点实验室,湖南省畜禽健康养殖工程技术研究中心,湖南,长沙410125
基金项目:国家自然科学基金项目,海外青年学者合作研究基金,中国科学院海外杰出学者基金项目 
摘    要:本文比较研究了日粮中添加精氨酸(L-Arginine,Arg)和精氨酸生素(Arginine activator additive,AAA)对早期断奶仔猪氧化应激的影响.试验选用84头21日龄断奶的长X大仔猪(5.56±0.07 kg),共12栏,分为3个处理组(4栏/处理,7头/拦).分别饲喂基础日粮(SD)、SD+AAA(0.08%)或SD+Arg(0.6%),试验期为7d.结果表明:与对照组相比,Arg和AAA添加组中血清Arg浓度、平均日增重(ADG)及肠道重均显著增加(P<0.05),血清皮质醇(COR)、丙二醛(MDA)及尿素氮(BUN)浓度显著降低(P<0.05);与对照相比,AAA添加组血清谷胱甘肽(GSH)水平显著增加(P<0.05),腹泻率、血清谷丙转氨酶(ALT)活性及肠粘膜MDA浓度显著降低(P<0.01),而Arg添加组中上述四者无显著变化,且Arg添加组中空肠黏膜GSH水平显著降低(P<0.01).与Arg添加组相比,AAA添加组中血清GSH、铜锌过氧化物歧化酶(CuZn-S00)及黏膜GSH显著增加(P<0.05),并且肠粘膜MDA降低了32.9%.因此,日粮添加AAA或Arg均促进断奶仔猪的生长性能的提高,缓解断奶引起的氧化应激,但与Arg相比,AAA不仅更有效降低了MDA的水平,而且提高了断奶仔猪的抗氧化系统功能,从而更好的缓解了氧化应激,缓解了肠黏膜的氧化损伤.

关 键 词:精氨酸  精氨酸生素  断奶仔猪  氧化应激

Effects of L-Arginine and Arginine Activator Additive on Oxidative Stress Caused by Weaning in Early-weaned Piglets
GAO Yun-ling,WU Xin,ZHOU Xi-hong,LI Tie-jun,GENG Mei-mei,HUANG Rui-lin and YIN Yu-long.Effects of L-Arginine and Arginine Activator Additive on Oxidative Stress Caused by Weaning in Early-weaned Piglets[J].Research of Agricultural Modernization,2010,31(4):484-487.
Authors:GAO Yun-ling  WU Xin  ZHOU Xi-hong  LI Tie-jun  GENG Mei-mei  HUANG Rui-lin and YIN Yu-long
Institution:Hunan Engineering and Research Center of Animal and Poultry Science,Key Laboratory of Agro-ecological Processes in Subtropical Region,Institute of Subtropical Agriculture,Chinese Academy of Sciences,Changsha,Hunan 410125,China;Graduate University of Chinese Academy of Sciences,Beijing 100049,China;Hunan Engineering and Research Center of Animal and Poultry Science,Key Laboratory of Agro-ecological Processes in Subtropical Region,Institute of Subtropical Agriculture,Chinese Academy of Sciences,Changsha,Hunan 410125,China;Graduate University of Chinese Academy of Sciences,Beijing 100049,China;Hunan Engineering and Research Center of Animal and Poultry Science,Key Laboratory of Agro-ecological Processes in Subtropical Region,Institute of Subtropical Agriculture,Chinese Academy of Sciences,Changsha,Hunan 410125,China;Graduate University of Chinese Academy of Sciences,Beijing 100049,China;Hunan Engineering and Research Center of Animal and Poultry Science,Key Laboratory of Agro-ecological Processes in Subtropical Region,Institute of Subtropical Agriculture,Chinese Academy of Sciences,Changsha,Hunan 410125,China;Hunan Engineering and Research Center of Animal and Poultry Science,Key Laboratory of Agro-ecological Processes in Subtropical Region,Institute of Subtropical Agriculture,Chinese Academy of Sciences,Changsha,Hunan 410125,China;Hunan Engineering and Research Center of Animal and Poultry Science,Key Laboratory of Agro-ecological Processes in Subtropical Region,Institute of Subtropical Agriculture,Chinese Academy of Sciences,Changsha,Hunan 410125,China;Hunan Engineering and Research Center of Animal and Poultry Science,Key Laboratory of Agro-ecological Processes in Subtropical Region,Institute of Subtropical Agriculture,Chinese Academy of Sciences,Changsha,Hunan 410125,China
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