Aminopyrifen,a novel 2-aminonicotinate fungicide with a unique effect and broad-spectrum activity against plant pathogenic fungi |
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Authors: | Masahiro Hatamoto Ryo Aizawa Kogomi Koda Toshiki Fukuchi |
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Institution: | 1.Biological Section Research Department, AGRO-KANESHO Co., Ltd., 9511–4, Yuki Ibaraki 307–0001, Japan;2.Chemical Synthesis Section Research Department, AGRO-KANESHO Co., Ltd., Tokorozawa, Saitama 359–0024, Japan |
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Abstract: | Aminopyrifen is a novel 2-aminonicotinate fungicide with unique chemistry and a novel mode of action. The fungicide showed high antifungal activity mainly against Ascomycetes and its related anamorphic fungi under in vitro and pot conditions (EC50 values: 0.0039–0.23 mg/L and 1.2–12 mg/L, respectively). The active ingredient strongly inhibited germ-tube elongation of Botrytis cinerea below 0.1 mg/L and invasion into a plant. The compound exhibited no cross-resistance to commercial fungicides in B. cinerea. The antifungal agent showed high preventive efficacy and translaminar action. In the field, aminopyrifen controlled gray mold and powdery mildew at 150 mg/L. Our findings suggest that aminopyrifen is useful for protecting crops from various plant pathogens. |
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Keywords: | aminopyrifen 2-aminonicotinate fungicide gray mold GPI GWT-1 inhibitor |
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