The effect of long-term exposure to phosphamidon on the ruminal microorganisms and circulating carboxylesterase ofBubalus bubalis |
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Authors: | M. A. Awal J. K. Malik |
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Affiliation: | (1) Department of Pharmacology, Bangladesh Agricultural University, 2202 Mymensingh, Bangladesh;(2) Department of Pharmacology, College of Veterinary Science & AH, 388001 Anand, India |
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Abstract: | The effect of long-term exposure to the organophosphate insecticide phosphamidon on the ruminal microorganisms and serum carboxylesterase of buffalo calves was investigated. Oral administration of phosphamidon in doses of 0.25 and 0.5 mg/kg per day for 120 days caused significant inactivation of carboxylesterase activity (16–32%) without eliciting any intoxicating signs apart from mild intermittent diarrhoea in the animals receiving the higher dose. The higher dose also produced a significant reduction in the total number of rumen protozoa (16–24%). However, the insecticide had no discernible effect on the total bacterial count or pH of the rumen liquor. |
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Keywords: | buffalo carboxylesterase microorganisms phosphamidon rumen serum toxicity |
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