用~(75)Se、~(65)Zn示踪研究微量元素硒、锌在家兔毛中沉积与体内代谢的关系

本研究以大耳白家兔为实验动物，分别用含硒，锌水平不同的饲粮预饲２个月后，每组５只动物各灌喂１次＾７５Ｓｅ－亚硒酸钠，＾６５Ｚｎ－硫酸锌溶液。测定了＾７５Ｓｅ，＾６５Ｚｎ的吸收，排泄与转移到毛中沉积的过程，实验末检测了各器官组织中了存留量。从测定背部被毛中的放射性变化的结果表明，＾７５Ｓｅ，＾６５Ｚｎ能较快的从体内转移到被行中，动物处理后第７ｄ和第５ｄ在背部被毛的基段和上段都测得了＾７５Ｓｅ和＾６５

STUDIES ON THE RELATIONSHIP BETWEEN TRACE ELEMENT=(SELENIUM,ZINC) ACCUMULATION IN HAIR AND METABOLISM IN BODY=OF RABBIT BY USING 75Se AND 65Zn TRACER TECHNIQUE

In this study,the rabbit was used as experimental animal.After 2 months of feeding the diet with different levels of Se or Zn, five animals from each group were given an oral dose of Na-275SeO-3 or 65ZnSO-4 solution,respectively.The process of absorption,exeretion,accumulation and transfer of istopes to the hair were determined,and the tissues retention of 75Se or 65Zn were also examined at the end of the experiments.The results obtained from the measurement of radioactive change of back hair in each group animal after the oral intake of 75Se or 65Zn showed that the 75Se or 65Zn transfer to hair were fast.At the seventh and fifth day after dosing,the 75Se or 65Zn were determined in the down|end section and upper|end section of back hair,and the radioactivity increased with time.At the first, the radioactivity in down|end section was higher than that of the upper|end section.However,at the end of experiment the upper|end section was higher than the down|end section.The data obtained from the different measuring point indicated that the accumulation,distribution of trace element in hair was not even,there was extended process from the down|end to the upper|end of hair and accumulation in upper|end section.The content of 75Se or 65Zn in hair was related to the level of Se or Zn in diet.However,there were difference among the different trace elements.