| 胚胎干细胞向神经细胞定向诱导分化方法的研究进展 |
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| 引用本文： | 薛亚梅,王锋.胚胎干细胞向神经细胞定向诱导分化方法的研究进展[J].中国畜牧杂志,2005,41(8):58-61. |
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| 作者姓名： | 薛亚梅 王锋 |
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| 作者单位： | 南京农业大学动物胚胎工程技术中心,江苏南京,210095 |
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| 基金项目： | 江苏省自然科学基金（BK2003075） |
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| 摘 要： | 胚胎干细胞具有自我更新和多向分化潜能,有望成为治疗神经系统疾病重要的种子细胞来源。如何高效地诱导胚胎干细胞向特定神经细胞分化是目前研究的热点。本文就胚胎干细胞定向分化成神经细胞的3种方法:RA诱导法、谱系选择法和SDIA法及其移植研究做一综述。
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| 关 键 词： | 畜牧、兽医科学基础学科 神经细胞 综述 诱导分化 胚胎干细胞 |
| 文章编号： | 0258-7033（2005）08-0058-03 |
| 收稿时间： | 2003-12-28 |
| 修稿时间： | 2004-04-05 |
Advance in Methods of Inducing Embryonic Stem Cells to Differentiate into Neural Cells |
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| XUE Ya-mei,WANG Feng.Advance in Methods of Inducing Embryonic Stem Cells to Differentiate into Neural Cells[J].Chinese Journal of Animal Science,2005,41(8):58-61. |
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| Authors: | XUE Ya-mei WANG Feng |
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| Abstract: | Embryonic stem (ES) cells are self-renewing and capable of multi-oriental differentiation. Therefore,they are expected to be an important seed cells resource for the treatment of nervous system diseases. How to induce ES cells efficiently to differentiate into special kind of neuronal cells becomes a hot spot of the recent research. This paper briefly reviews the three methods of ES cells differentiation toward neural lineages which include retinoic acid induction, lineage selection,and SDIA, and the transplantation therapies. |
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| Keywords: | basal disciplines of animal and veterinary science neural cell a review induced differentiation embryonic stem call |
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