长沙地区城镇居民迟发性性腺功能减退症发病调查分析

目的 了解长沙地区城镇居民迟发性性腺功能减退症（late-onset hypogonadism，LOH）发生率及影响因素。方法 选取健康男性志愿者295例，年龄40~70岁之间，调查采用个人信息、整体健康状况、男性更年期自我评定量表进行评估，并测定性激素水平，同时测定同一地区30~39岁健康男性的相关指标作为对照。结果 LOH量表筛查阳性率为37.29%，睾酮切点值（TT、FT、Bio-T）筛查总阳性率分别为19.66%、33.22%、27.12%，LOH临床患病率为10.85%。年龄、体质量指数、高血压、吸烟是影响LOH发病的重要危险因素，而有规律运动是LOH的重要保护性因素。结论 长沙地区城镇居民LOH发生率较高，年龄、整体健康状况及生活方式均是影响LOH的重要因素。

Investigation of Late-Onset Hypogonadism Incidence in Changsha Area

Objective To investigate the prevalence of late-onset hypogonadism and their related factors in old and middle-aged males in the town resident of Changsha area. Methods 295 healthy old and middle-aged(40-70 years old) males were colleted. The personal data and general health status and results of the questionnaire investigation were investigated using the Bosphorus scale. The concentrations of serum sex hormone were determined. Meanwhile, 30-39 years old males from the same area were as a control group. Results The screening positive rate of Bosphorus scale was 37.29%, according to T (TT, FT, Bio-T) cut-off point, the positive rate was 19.66%, 33.22%, 27.12%, late-onset hypogonadism prevalence rate was 10.85%. The main risk factors of late-onset hypogonadism included age, BMI, hypertension, smoking, but physical exercise was an important protective factor. Conclusion Late-onset hypogonadism prevalence rate of Changsha area was relative high. Age, general health status and life-style are closely associated with the prevalence of late-onset hypogonadism.