| 原发性肾病综合征34例临床和病理分析 |
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| 引用本文： | 刘华锋,黄萍萍,梁东,司徒玉,司徒洁,张肇,唐德.原发性肾病综合征34例临床和病理分析[J].湛江医学院学报,1999,17(2):113-115. |
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| 作者姓名： | 刘华锋 黄萍萍 梁东 司徒玉 司徒洁 张肇 唐德 |
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| 作者单位： | 广东医学院肾脏疾病研究所 |
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| 摘 要： | 目的：为了加深对成人原发性肾病综合征的认识，进一步提高对本病的诊疗水平。方法：收集１９９７年１２月－１９９８年１０月住院成人原发性肾病综合征（ＰＮＳ）３４例进行分析研究。结果：系膜增生性肾小球肾炎在本组中占５８．８％，是最常见病理类型。微小病变（ＭＣＤ）较非微小病变（ｎ－ＭＣＤ）有明显的尿蛋白，低蛋白血症和高脂血症；膜尿蛋白的选择性与病理类型及疗效无关，不能用于估计病理类型及治疗效果。
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| 关 键 词： | 肾变病综合征 病理学 蛋白尿 治疗 肾小管-间质损害 并发症 |
| 修稿时间： | 1999-02-01 |
Analysis of clinical features and pathology in 34 patients with primary nephrotic syndrome |
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| LiuHuafeng,HuangPingping,LiangDong,etal.Analysis of clinical features and pathology in 34 patients with primary nephrotic syndrome[J].Journal of Guangdong Medical College,1999,17(2):113-115. |
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| Authors: | LiuHuafeng HuangPingping LiangDong etal |
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| Abstract: | Objective: Toinvestigatetheadultprimarynephroticsyndrome(PNS)forimprovingthelevelofdiagnosisandtherapyofPNS. Methods: Thedataof34casesofPNSfromDecember,1997toNovember,1998wereanalysed. Results: Mesangialproliferativeglomerulonephritis(MesPGN)wasthemostgeneralpathologictypeofPNSandtheratewas58.8%.Minimalchangedisease(MCD)hadaheavierproteinuria,hypoalbuminemiaandhyperlipdemiathanthatinnonMCD(nMCD).Patientswithmebranousnephropathy(MD)had higher chance ofinfectionandrenalswellinginthisseries.Thetotaleffectiveratewas89.2%withstanderdtherapyofprednison,andtheeffectofMCDwasthebest. Conclusion: Theselectivityofproteinuriahavenotrelevancetopathologictypesandcurativeeffect.Tubularinterstitialinjury(TII)wascloselyrelatedtotheeffect,andurineRBPwasagoodpredictorofTII. |
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| Keywords: | nephroticsyndrome pathology proteinuria therapy tuberlarinterstitialinjury complication |
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