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Single-cell transcriptomic atlas of goat ovarian agingOA
作者姓名:Dejun Xu  Shuaifei Song  Fuguo Wang  Yawen Li  Ziyuan Li  Hui Yao  Yongju Zhao  Zhongquan Zhao
基金项目:supported by the National Key Research and Development Program of China (2022YFD1300202);;the National Natural Science Foundation of China (32102623);;the National Natural Science Foundation of Chongqing (cstc2021jcyj-msxm X0875);
摘    要:Background The ovaries are one of the first organs that undergo degenerative changes earlier in the aging process, and ovarian aging is shown by a decrease in the number and quality of oocytes. However, little is known about the molecular mechanisms of female age-related fertility decline in different types of ovarian cells during aging, especially in goats. Therefore, the aim of this study was to reveal the mechanisms driving ovarian aging in goats at single-cell resolution.Results For the firs...

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