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蛋鸡的胆固醇代谢调控研究进展
引用本文:汪仕奎,佟建明.蛋鸡的胆固醇代谢调控研究进展[J].动物营养学报,2002,14(3):7-11.
作者姓名:汪仕奎  佟建明
作者单位:中国农业科学院畜牧研究所 北京100094 (汪仕奎),中国农业科学院畜牧研究所 北京100094(佟建明)
摘    要:胆固醇是生命活动的必需物质 ,但大量摄入又是导致心血管疾病的重要因素。利用营养和分子生物学手段对蛋鸡的胆固醇代谢过程进行研究 ,有利于找到降低鸡蛋中胆固醇含量的措施。蛋鸡体内胆固醇合成途径与哺乳动物相同 ,但转运过程存在很大区别。研究发现不饱和脂肪酸、粗纤维、植物固醇和药物等对鸡蛋胆固醇含量有重要影响 ,HMG -CoA还原酶抑制剂是一类作用效果最为明显的调控物

关 键 词:蛋鸡  胆固醇代谢  调控  HMG-CoA还原酶抑制剂
文章编号:1006-267X(2002)03-0007-05
修稿时间:2001年8月29日

REVIEW IN MANIPULATION OF CHOLESTEROL METABOLISM IN LAYING HENS
WANG Shi-kui,TONG Jian-ming.REVIEW IN MANIPULATION OF CHOLESTEROL METABOLISM IN LAYING HENS[J].Acta Zoonutrimenta Sinica,2002,14(3):7-11.
Authors:WANG Shi-kui  TONG Jian-ming
Abstract:Cholesterol is essential to life activity,but dietary cholesterol abounding in eggs has been suggested to increase the risk of human cardiovascular diseases.In order to decrease the cholesterol in the yolk,the cholesterol metabolism of laying hens has been studied by nutritional and biochemical ways.There is no difference of cholesterol biosynthesis between mammalian and laying hens,but the transportation of cholesterol is evidently different between them.By far,the HMG-CoA reductase inhibitors have been proved to be very effective while many manipulators,such as PUFA,dietary fiber,plant sterol and hers,have been reported to decrease the concentration of cholesterol in the yolk.
Keywords:laying hens  cholesterol metabolism  manipulation  HMG-CoA reductase inhibitors
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