| 半边旗5F对兔耳增生性瘢痕组织的影响 |
| |
| 引用本文： | 陈萍,吴志远,罗少军,汤少明,江黎明.半边旗5F对兔耳增生性瘢痕组织的影响[J].湛江医学院学报,2006,24(2):112-112,118. |
| |
| 作者姓名： | 陈萍 吴志远 罗少军 汤少明 江黎明 |
| |
| 作者单位： | 广东医学院附属医院整形外科研究所,广东湛江524001;广东医学院附属医院中心实验室,广东湛江524001 |
| |
| 摘 要： | 目的:观察半边旗5F对兔耳增生性瘢痕组织的影响。方法:建立兔耳增生性瘢痕动物模型,21d时瘢痕局部注射不同浓度(20,40,80 m g/L)的半边旗5F或生理盐水,28d时观察药物对瘢痕增生指数(H I)的影响及光镜下瘢痕变化情况。结果:各浓度组与生理盐水对照组以及各浓度组之间H I差异均有显著性意义(P<0.01);其瘢痕抑制效果与半边旗5F浓度呈剂量依赖性关系;光镜下见明显抑制成纤维细胞增殖及降低胶原纤维的含量。结论:半边旗5F可抑制兔耳增生性瘢痕组织增生。
|
| 关 键 词： | 半边旗 增生性瘢痕 动物模型 |
| 文章编号： | 1005-4057（2006）02-0002-02 |
| 收稿时间： | 11 28 2005 12:00AM |
| 修稿时间： | 2005-11-282006-03-13 |
Effects of Pteris Semipinnata 5F on the hypertrophic scar on rabbit ears |
| |
| CHEN Ping,WU Zhi-yuan,LUO Shao-jun,TANG Shao-min,JIANG Li-min.Effects of Pteris Semipinnata 5F on the hypertrophic scar on rabbit ears[J].Journal of Guangdong Medical College,2006,24(2):112-112,118. |
| |
| Authors: | CHEN Ping WU Zhi-yuan LUO Shao-jun TANG Shao-min JIANG Li-min |
| |
| Institution: | Department of Plastic Surgery, Guangdong Medical College,Zhanjiang 524001, China |
| |
| Abstract: | Objective: To observe the effects of Pteris Semipinnata 5F on the hypertrophic scar on rabbit ears.Methods: Hypertrophic scars made on rabbit ears were injected with Pteris Semipinnata 5F at concentrations(20,40,80mg/L) or saline as control at day 21 started from the scars were made.At day 28 the rabbits were killed to observe hypertrophic index(HI) and morphological change of scars.Results: Compared with the control group,Pteris Semipinnata 5F significantly reduced HI in a dosage dependent manner(P<0.05).The proliferation of fibroblast and collagen decreased in the Pteris Semipinnata 5F treated group.Conclusion: Pteris Semipinnata 5F could inhibit proliferation of hypertrophic scars on rabbit ears. |
| |
| Keywords: | Pteris Semipinnata 5F hypertrophic scar rabbit |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
