Hypolipidemic effect in cholesterol-fed rats of a soluble fiber-rich product obtained from cocoa husks |
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Authors: | Ramos Sonia Moulay Leila Granado-Serrano Ana Belén Vilanova Olga Muguerza Begoña Goya Luis Bravo Laura |
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Institution: | Department of Metabolism and Nutrition, Instituto del Frio, Spanish Council for Scientific Research (CSIC), C/ Jose Antonio Novais 10, 28040 Madrid, Spain. |
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Abstract: | A new soluble cocoa fiber product (SCFP), obtained after enzymatic treatment of cocoa husks, was characterized and its potential health effects studied in an animal model of dietary-induced hypercholesterolemia. The SCFP was rich in soluble dietary fiber (DF) and antioxidant polyphenols. Consumption of a cholesterol-rich diet containing the SCFP as a source of DF resulted in lower food intake and body weight gain in comparison with control groups consuming cholesterol-free or cholesterol-rich diets with cellulose as DF. The cholesterol-rich diet caused remarkable hypercholesterolemia. However, the SCFP diminished the negative impact of the cholesterol-rich diet, buffering the decrease of high density lipoprotein-cholesterol, and the increase of total and low density lipoprotein-cholesterol levels, and lipid peroxidation (malondialdehyde levels) induced by the fatty diet. The SCFP also decreased triglyceride levels to values lower than those in the group fed the cholesterol-free diet. These results put forward the potential application of the SCFP as a dietary supplement or functional food ingredient. |
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