Physicochemical characterization and biological effects of inulin enzymatically synthesized from sucrose |
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Authors: | Wada Tadashi Sugatani Junko Terada Etsuko Ohguchi Masao Miwa Masao |
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Affiliation: | Fuji Nihon Seito Corporation, 1-4-10 Shimizuseikai, Shizuoka City, Shizuoka 424-8737, Japan. |
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Abstract: | We first developed the method to produce inulin from sucrose using an enzyme from Bacillus sp. 217C-1. Synthesized inulin consists of a linear polymer having beta(2-1) linkages of d-fructose with one terminal glucose. The synthesized inulin has similar properties (pH and thermal stability, Maillard reaction, and in vitro fermentation) to plant-derived inulin. The marked difference is the polydispersity of the inulin chain length. Synthesized inulin with a narrow degree range of fructose polymerization shows better solubility in water than plant-derived inulin. Synthesized inulin (5%, w/w) treatment for 12 weeks reduced the elevation in body weight and serum and liver lipids in rats fed high fat- and high sucrose-supplemented diets, and blood glucose in rats fed a standard diet. Synthesized inulin (15%, w/w) significantly suppressed the elevation in blood glucose of human healthy subjects after dextrin loading. These results suggest that daily intake of synthesized inulin modulates carbohydrate and lipid metabolism. |
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