Nuclear gene indicates coat-color polymorphism in mammoths |
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Authors: | Römpler Holger Rohland Nadin Lalueza-Fox Carles Willerslev Eske Kuznetsova Tatyana Rabeder Gernot Bertranpetit Jaume Schöneberg Torsten Hofreiter Michael |
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Affiliation: | Molecular Biochemistry, Institute of Biochemistry, Medical Faculty, University of Leipzig, 04103 Leipzig, Germany. |
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Abstract: | By amplifying the melanocortin type 1 receptor from the woolly mammoth, we can report the complete nucleotide sequence of a nuclear-encoded gene from an extinct species. We found two alleles and show that one allele produces a functional protein whereas the other one encodes a protein with strongly reduced activity. This finding suggests that mammoths may have been polymorphic in coat color, with both dark- and light-haired individuals co-occurring. |
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