Abstract: | There is no reaction-basis for the division of the process of blood-coagulation into the two stages (transparent and opaque) which appearso strikingly in sloiwly-clotting mammalian blood. These stages are saperficial phenomena which merely reflect the extent of fibrin-formation. Coagulation is a gradual continuous process of fibrin-formation; and in the clotting of normal plasma, fibrin needles can be demonstrated in the earliest appreciable coagulum, however delicate, transparent or gellike. |