Severe Leukemoid Response Associated With Mycobacterium genavense Infection in a Pet Budgerigar (Melopsittacus undulatus) |
| |
Authors: | Michelle Sutherland Natalie Courtman Philip Sacks Patricia Macwhirter |
| |
Affiliation: | 1. Burwood Bird and Animal Hospital, Burwood, Vic, Australia;2. Department of Veterinary Clinical Pathology, The University of Melbourne Veterinary Hospital, Werribee, Vic, Australia. |
| |
Abstract: | A 2-year-old pet budgerigar was presented after a period of general malaise that was unresponsive to supportive therapy. Radiographic images revealed a marked hepatomegaly. Hematology results indicated the bird had a severe leukocytosis with marked discrepancy between the hemocytometer white blood cell (WBC) count and WBC estimated from the smear. The leukocytosis was characterized by an extreme heterophilia with marked left shift, including the presence of metamyelocytes and promyelocytes with marked toxic changes, and a marked monocytosis, consistent with a leukemoid response. The bird died despite supportive treatment. Hepatosplenomegaly was present at necropsy. Histopathology of multiple tissues demonstrated acid-fast organisms on Ziehl-Neelsen staining, subsequently identified as Mycobacterium genavese by polymerase chain reaction analysis. Mycobacteriosis should be considered as a differential diagnosis in the presence of a severe leukemoid response with multiple heterophilic precursors in avian species. |
| |
Keywords: | mycobacteriosis leukemoid response budgerigar Address correspondence to: Michelle Sutherland, BVM&S, MANZCVS (Avian Health), CertAVP (ZooMed) MRCVS, Burwood Bird and Animal Hospital, 128 Highbury Rd, Burwood, Vic 3125, Australia. |
本文献已被 ScienceDirect 等数据库收录! |
|