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ND-EDS-76异源二联油苗的研制
引用本文:贾英科,高梅秀,崔学艺.ND-EDS-76异源二联油苗的研制[J].西北农林科技大学学报(社会科学版),2001,29(2):29-32.
作者姓名:贾英科  高梅秀  崔学艺
作者单位:1. 天津农学院动科系,
2. 农业部郑州生物药厂,
基金项目:天津市自然科学基金资助项目(933611911)
摘    要:将鸭源鸡新城疫 (ND)病毒 D1 0 株和鸡减蛋综合症 (EDS- 76 )病毒 GC2 株同时接种于同一鸭胚内复制 ,增殖 96 h收取尿囊液 ,用甲醛灭活后加白油佐剂制成 ND- EDS- 76异源二联油乳剂灭活疫苗。该疫苗生产工艺简单 ,成本低 ,经试用表明可有效地预防 ND和 EDS- 76的发生。

关 键 词:鸡新城疫  鸡减蛋综合症  异源二联油乳剂灭活疫苗  油苗研制
文章编号:1000-2782(2001)02-029-04
收稿时间:2000/11/6 0:00:00
修稿时间:2000年11月6日

Study on oil emulison inactivated duck origin ND-EDS-76 bivalent combined vaccine
JIA Ying-ke,GAO Mei-xiu,CUI Xue-yi,ZHANG Ju-zhou,XIONG Feng.Study on oil emulison inactivated duck origin ND-EDS-76 bivalent combined vaccine[J].Journal of Northwest Sci-Tech Univ of Agr and,2001,29(2):29-32.
Authors:JIA Ying-ke  GAO Mei-xiu  CUI Xue-yi  ZHANG Ju-zhou  XIONG Feng
Institution:JIA Ying- ke1,GAO Mei- xiu1,CUI Xue- yi2,ZHANG Ju- zhou2,XIONG Feng2
Abstract:Duck origin ND.D10 strain and EDS-76GC2 strain were inoculated into the same duck embryos and harvested after96hours of culture.The propagated virus were inactivated by formalin and mingled with oil emulsion adjuvant according to rational rate,and a combined inactivated oil- adjuvant duck origin NDV and EDS- 76vaccine was developed,which simplified the production process and reduced production cost.The tests of vaccine safety,antibody response,protective rate and duration of immunity were also preformed.The results show that this kind of vaccine could prevent ND virus and EDS- 76virus infection successfully.
Keywords:newcastle disease  egg drop syndrome(EDS- 76)  oil emulsion inactivated duck origin ND-  EDS- 76bivalend vaccin  oil emulision production  
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