胰岛素和酶解配方奶粉对初生仔猪小肠生长发育的影响

为研究胰岛素和酶解配方奶粉是否促进初生仔猪小肠的组织生长和功能成熟，本试验比较了饲喂配方奶粉与饲喂配方奶粉补加胰素或酶解配方奶粉３ｄ后仔猪小肠的重量和长度，组织形态学结构，粘膜ＤＮＡ，ＲＮＡ和蛋白质含量，及小肠内容物中乳糖酶，麦芽糖酶和碱性磷酸酶活性。

EFFECTS OF ORAL INSULIN AND TRYPSINIZED FORMULA MILK ON SMALL INTESTINAL GROWTH AND DEVELOPMENT IN NEWBORN PIGS

To study whether insulin in milk and trypsinized formula milk are responsible for the rapid postnatal tissue growth and functional maturation in the small intestine of newborn pigs,small intestinal tissue mass,length tissue structure,mucosal DNA,RNA and protein contents,and lactase,maltase and alkaline phosphatase activities in the small intestinal tissue contents between piglets bottle fed formula milk(Milk)and piglets bottle fed either formula milk supplemented with insulin(60mIU/ml)(IMilk)or trypsinized formula milk(TMilk)for 3 days were compared.There were no significant differences in the small intestinal tissue mass,length,tissue structure,and mucosal DNA and RNA contents( P >0 05)of piglets fed IMilk or TMilk compared with those of piglets fed Milk.The mucosal weight( P <0 05) and protein content( P <0 01)in the small intestine,specifically in the distal ileum( P <0 01),in IMilk fed piglets were greater than those in Milk fed piglets.Total activities of lactase,maltase and alkaline phosphatase in the small intestinal contents of TMilk fed piglets( P <0 01)increased significantly in comparison with those of Milk fed piglets.The results indicate that oral administration of insulin stimulates a increase in mucosal weight and protein content in the small intestine,specifically in the distal ileum,and total activities of lactase,maltase and alkaline phosphatase in the small intestinal contents.The trypsinized formula milk contains some bioactive substance that can stimulate the newborn intestinal development.