Analgesic and antipyretic effects of Capparis zeylanica leaves |
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Authors: | Ghule B V Murugananthan G Yeole P G |
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Institution: | Institute of Pharmaceutical Education and Research, Borgaon, Wardha, MS, India. dr_yeole@rediffmail.com |
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Abstract: | The ethanol and water extracts of Capparis zeylanica leaves showed dose-dependent and significant (P<0.05) increases in pain threshold in tail-immersion test. Moreover, both the extracts (100-200 mg/kg) exhibited a dose-dependent inhibition of writhing and also showed a significant (P<0.001) inhibition of both phases of the formalin pain test. The water extract (200 mg/kg) significantly (P<0.01) reversed yeast-induced fever. Preliminary phytochemical screening of the extracts showed the presence of alkaloids, flavonoids, saponins glycosides, terpenoids, tannins, proteins and carbohydrates. |
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Keywords: | Capparis zeylanica Analgesic activity Antipyretic activity |
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