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Hyperthyroidism in four guinea pigs: clinical manifestations,diagnosis, and treatment
Authors:F. Künzel  B. Hierlmeier  M. Christian  M. Reifinger
Affiliation:1. Clinical Department for Companion Animals and Horses, University of Veterinary Medicine Vienna, , 1210 Vienna, Austria;2. Department for Pathology, University of Veterinary Medicine Hannover, , 30559 Hannover, Germany;3. LABOKLIN, Laboratory for Clinical Diagnostics, , 4040 Linz, Austria;4. Department for Pathobiology, University of Veterinary Medicine Vienne, , 1210 Vienna, Austria
Abstract:Hyperthyroidism was diagnosed in four guinea pigs by demonstration of an increased serum total thyroxine concentration. The main clinical signs were comparable with those observed in feline hyperthyroidism and included weight loss despite maintenance of appetite and a palpable mass in the ventral cervical region. Three animals were treated successfully with methimazole for between 13 and 28 months. Clinical signs and regular measurement of circulating total thyroxine concentrations appear to be convenient parameters for monitoring response to medical therapy.
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