|
|||||
|
|
| 中国部分绵羊品种BMPR-IB基因RFLP多态性的研究 | |
| 引用本文： | 刘凤丽,刘永斌,王峰,王瑞,田春英,刘美霞,魏建民,荣威恒.中国部分绵羊品种BMPR-IB基因RFLP多态性的研究[J].华北农学报,2007,22(4):151-154. |
| 作者姓名： | 刘凤丽 刘永斌 王峰 王瑞 田春英 刘美霞 魏建民 荣威恒 |
| 作者单位： | 1. 内蒙古农业大学,生物工程学院,内蒙古,呼和浩特,010018 2. 内蒙古农业大学,生物工程学院,内蒙古,呼和浩特,010018;内蒙古农牧业科学院,内蒙古,呼和浩特,010030 3. 内蒙古农牧业科学院,内蒙古,呼和浩特,010030 4. 内蒙古医学院第二附属医院,内蒙古,呼和浩特,010010 |
| 基金项目： | 国家自然科学基金资助项目(30560102) |
| 摘 要： | 为了研究骨形态发生蛋白受体(BMPR-IB)基因对绵羊排卵控制的作用,进一步寻找与多胎绵羊相关的遗传标记,为中国地方绵羊品种繁殖性状的标记辅助选择提供一定的理论基础。以影响Booroola Merino高产性能的BM-PR-IB基因为候选基因,采用PCR-RFLP方法分析内蒙古地方品种,蒙古羊、呼伦贝尔羊、内蒙古细毛羊与中国美利奴多胎品系共206只绵羊个体的基因多态性,以及BMPR-IB基因多态性与绵羊进化的关系。结果表明:高繁殖力的中国美利奴羊多胎品系BMPR-IB基因编码序列第746位碱基处发生了与Booroola Merino绵羊相同的突变(A746G),而低繁殖力的蒙古羊、呼伦贝尔羊、内蒙古细毛羊则没有发生这种突变。 |
| 关 键 词： | 绵羊 基因多态性 骨形态发生蛋白受体IB基因 PCR-RFLP |
| 文章编号： | 1000-7091（2007）04-0151-04 |
| 修稿时间： | 2007-03-30 |
Study on the Polymorphism of Bone Morphogenetic Protein Receptor IB in China Partial Sheep |
|
| LIU Feng-li,LIU Yong-bin,WANG Feng,WANG Rui,TINA Chun-ying,LIU Mei-xia,WEI Jian-min,RONG Wei-heng.Study on the Polymorphism of Bone Morphogenetic Protein Receptor IB in China Partial Sheep[J].Acta Agriculturae Boreali-Sinica,2007,22(4):151-154. | |
| Authors: | LIU Feng-li LIU Yong-bin WANG Feng WANG Rui TINA Chun-ying LIU Mei-xia WEI Jian-min RONG Wei-heng |
| Institution: | 1. College of Biological Engineering, Inner Mongolian Agricultural University, Huhhot 010018, China; 2. Inner Mongolia Academy of Agriculture and Husbandry Sciences, Huhhot 010010, China; 3. The Second Accessory Hospital,Academy of Inner Mongolia Medicine Science, Huhhot 010010, China |
| Abstract: | In order to study function of BMPR-IB on sheep ovulation control and to find the genetic marker of multi fetus sheep,bone morphogenetic protein receptor IB(BMPR-IB) gene which controled fecundity of Boorola Merino ewes was studied as a candidate gene on the prolificacy in mongolian ewes and china Merino.Single nucleotide polymorphism of BMPR-IB gene was determined in high fecundity sheep breeds(china merino)and low fecundity sheep breeds(mongolian sheep,hulunbeier sheep,Inner mongolian fine wool sheep) by PCR-RFLP.The results indicated that there was a same mutation(A746G) of BMPR-IB gene in china Merino as that in Booroola Merino ewes.The mutation did not exist in mongolian sheep,hulunbeier sheep,Inner Mongolian fine woolsheep. |
| Keywords: | Sheep Gene polymorphism BMPR-IB gene PCR-RFLP |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |