Two New Bromophenols with Radical Scavenging Activity from Marine Red Alga Symphyocladia latiuscula |
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Authors: | Xiuli Xu Liyuan Yin Lijie Gao Junhai Gao Junhui Chen Jingxi Li Fuhang Song |
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Affiliation: | 1.School of Ocean Sciences, China University of Geosciences, Beijing 100083, China; E-Mails: (L.Y.); (L.G.); (J.G.);2.Marine Ecology Research Center, First Institute of Oceanography, State Oceanic Administration, Qingdao 266061, China; E-Mails: (J.C.); (J.L.) ;3.Chinese Academy of Sciences Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100190, China |
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Abstract: | Chemical investigation of a Chinese collection of marine red alga Symphyocladia latiuscula yielded two new highly brominated phenols. The structures of the new compounds were elucidated by detailed spectroscopic analysis, including HRMS, 1D and 2D NMR and MS methods. Compounds 1 and 2 were evaluated for radical scavenging capability by 1,1-diphenyl-2-picrylhydrazuyl (DPPH) radical with the IC50 value of 14.5 and 20.5 μg/mL, respectively. |
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Keywords: | red alga Symphyocladia latiuscula bromophenol |
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