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Two New Bromophenols with Radical Scavenging Activity from Marine Red Alga Symphyocladia latiuscula
Authors:Xiuli Xu  Liyuan Yin  Lijie Gao  Junhai Gao  Junhui Chen  Jingxi Li  Fuhang Song
Institution:1.School of Ocean Sciences, China University of Geosciences, Beijing 100083, China; E-Mails: (L.Y.); (L.G.); (J.G.);2.Marine Ecology Research Center, First Institute of Oceanography, State Oceanic Administration, Qingdao 266061, China; E-Mails: (J.C.); (J.L.) ;3.Chinese Academy of Sciences Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100190, China
Abstract:Chemical investigation of a Chinese collection of marine red alga Symphyocladia latiuscula yielded two new highly brominated phenols. The structures of the new compounds were elucidated by detailed spectroscopic analysis, including HRMS, 1D and 2D NMR and MS methods. Compounds 1 and 2 were evaluated for radical scavenging capability by 1,1-diphenyl-2-picrylhydrazuyl (DPPH) radical with the IC50 value of 14.5 and 20.5 μg/mL, respectively.
Keywords:red alga  Symphyocladia latiuscula  bromophenol
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